A Joint Commission-accredited organization must review its formulary annually to ensure what?

The correct choice emphasizes the critical review of both efficacy and safety of the medications included in the formulary. For organizations accredited by the Joint Commission, maintaining a formulary that is evaluated annually is essential to ensure that the medications provided to patients are both effective in treating their conditions and safe for use.

Efficacy pertains to how well a medication works in achieving its desired outcome in the intended population. Safety refers to the absence of harmful effects or the minimization of risk associated with the medication's use. Regular reviews help to identify any emerging safety concerns, changes in clinical guidelines, or new evidence regarding the effectiveness of existing medications. By focusing on both of these aspects, the organization can optimize treatment options for patients while safeguarding their health.

Other factors like cost and effectiveness are important considerations in a healthcare setting, but they do not capture the primary goals of formulary reviews in the context set by the Joint Commission, which are ensuring that medications are proven to be effective and safe for patient use.